Alternative Names: Inositol Nicotinate or Hexanicit.
Inositol Hexaniacinate (also known as inositol hexanicotinate) is a newer form of vitamin B-3 (niacin), which does not cause flushing.
Function; Why it is Recommended
When six niacin
molecules are bound to a large molecule of inositol
, inositol hexaniacinate is the result. Inositol hexaniacinate delivers niacin in a natural slow-release manner, allowing for all the cholesterol-modulating benefits of niacin with little potential for side-effects such as flushing (itching, heat and redness in the skin) or liver
damage. Preliminary research has shown that inositol hexaniacinate has similar actions to niacin.Inositol
hexaniacinate is used primarily as flush-free niacin
, having the same cholesterol-lowering abilities as niacin without the flushing common to high-dose niacin therapy. Inositol hexaniacinate is safely substituted for niacin in conditions such as hypercholesterolemia
and intermittent claudication
hexanicotinate doses are similar to those of niacin
, about 600 to 3,000mg daily. However, the amount of research studying the safety of inositol hexaniacinate remains limited. Therefore, if you are considering taking this supplement in amounts over several grams per day you should be under a doctor's care.