What Causes Abnormal Total Iron Binding Capacity?
Abnormal total iron binding capacity can have various causes, ranging in severity from 'needs attention' to 'life-threatening'. Finding the true cause means ruling out or confirming each possibility – in other words, diagnosis.
Diagnosis is usually a complex process due to the sheer number of possible causes and related symptoms. In order to diagnose abnormal total iron binding capacity, we could:
- Research the topic
- Find a doctor with the time
- Use a diagnostic computer system.
The process is the same, whichever method is used.
Step 1: List all Possible Causes
We begin by identifying the disease conditions which have "abnormal total iron binding capacity" as a symptom. Here are three possibilities:
- Iron Deficiency Anemia
- Cirrhosis Of The Liver
Step 2: Build a Symptom Checklist
We then identify all possible symptoms and risk factors of each possible cause, and check the ones that apply:
frequent severe abdominal pain
white inside lower eyelids
high serum iron
very low ferritin levels
low sperm count
being medication sensitive
minimal body hair
darker/redder skin color
... and more than 20 others
Step 3: Rule Out or Confirm each Possible Cause
A differential diagnosis of your symptoms and risk factors finds the likely cause of abnormal total iron binding capacity:
|Cirrhosis Of The Liver
|Iron Deficiency Anemia
* This is a simple example to illustrate the process
Arriving at a Correct Diagnosis
is our online diagnosis tool that learns all about you through a straightforward process of multi-level questioning, providing diagnosis at the end.
Iron, TIBC (Total Iron Binding Capacity). Unit: ug/dL [umol/L]
→ Don't know
→ Under 150 [26.9]
→ 150-239 [26.9-42.8]
→ 240-450 [42.9-80.6] (normal)
→ Over 450 [80.6]
Based on your response to this question, which may indicate very low TIBC, low TIBC, normal TIBC or elevated TIBC, The Analyst™
will consider possibilities such as:
Hemochromatosis (Iron overload)
|While low TIBC is commonly explained by the presence of hemochromatosis, it can also be caused by hypoproteinemia from malnutrition, anemia with infection and chronic disease, and nephrosis.|Iron Deficiency Anemia
|While TIBC is commonly elevated in cases of iron deficiency anemia, it is also increased through the use of oral contraceptives and in pregnancy, blood loss and acute liver damage.|
... and also rule out issues such as: