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Poor/Slow Wound Healing
| Curcumin is an extract of the spice turmeric, known to have antioxidant properties and other health benefits. In Indian medicine, curcumin is used to reduce inflammation and treat wounds and skin ulcers. Topical application of curcumin encourages wound remodeling via effects on transforming growth factor-beta (TGF-b). It also improves reepitheliazation (new skin formation) and migration of cells such as myofibroblasts, fibroblasts, and macrophages, necessary for healing at the wound site. |
Chronic Inflammation
| Curcumin comes from the spice turmeric. The rhizome of this plant has been traditionally used as an antiinflammatory agent in Ayurvedic medicine. Curcumin appears to reduce proinflammatory leukotriene synthesis and also promotes the breakdown of fibrin. In a double-blinded trial, patients receiving 1,200mg of curcumin per day experienced reductions in stiffness and joint swelling comparable to the effects of phenylbutazone, a potent antiinflammatory drug. Curcumin has also reduced inflammation in surgical patients. |
Rheumatoid Arthritis
| Clinical studies have substantiated curcumin anti-inflammatory effects, including a significant beneficial effect in Rheumatoid Arthritis. In one study, curcumin was compared to phenylbutazone, a very potent NSAID that has fallen out of favor because of frequent side effects. The improvements in the duration of morning stiffness, walking time, and joint swelling were comparable in both groups. |