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5-HIAA Urine test
  5-HIAA Urine test
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5-HIAA (5-hydroxy indole acetic acid) is the main breakdown product of serotonin. The quantitative measurement in the urine that an individual excretes in a 24-hour period indicates how much serotonin is being made in the body during that time. Directions


Certain foods and medicines must be avoided for a day or two before, and on the day of, the urine collection, since they can cause false test results. These are bananas, pineapple and its juice, red plums, avocado, walnuts, kiwi fruit, tomatoes, various cough medicines, muscle relaxing medicines, acetaminophen (Tylenol), caffeine, fluorouracil, iodine solutions, phenacetin, MOA inhibitors (certain antidepressant drugs), isoniazid and phenothiazine drugs (Compazine, Thorazine).





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Tumors, MalignantIcon  Carcinoid Cancer
SpacerWhy In the presence of Carcinoid Syndrome the amount of 5-HIAA is almost always distinctly increased above normal.
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KEY
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GLOSSARY

Antidepressant (Antidepressants)
Literally, substances meant to oppose depressions or sadness, and generally heterocyclic types such as Elavil, MAO inhibitors like phenelzine, or lithium carbonate. This category of substances formerly included stuff like amphetamines and other stimulants. Botanical examples include Hypericum, Peganum and Oplopanax.

Iodine
A essential mineral that is an integral part of the thyroid hormones, thyroxin and triiodothyronine which have important metabolic roles and govern basal metabolism. The best known iodine deficiency symptom is goiter. Other iodine deficiency problems are reduced vitality, hypothyroidism, inability to think clearly, low resistance to infection, loss of control of the muscles of the mouth resulting in mouth contortion and drooling, defective teeth, tendency to obesity and cretinism which is a congenital abnormal condition marked by physical stunting and mental deficiency.

Serotonin
A phenolic amine neurotransmitter (C10H12N2O) that is a powerful vasoconstrictor and is found especially in the brain, blood serum and gastric membranes of mammals. Considered essential for relaxation, sleep, and concentration.

Syndrome
A medical condition characterized by a collection of related symptoms (what the patient feels) and signs (what a doctor can observe or measure).




Last updated: Jan 03, 2010


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