Low-Density Lipoprotein

Definition of Low-Density Lipoprotein:

Also known as "bad" cholesterol, LDLs are large, dense, protein-fat particles composed of a moderate proportion of protein and a high proportion of cholesterol.  Higher levels of LDLs are associated with a greater risk of cardiovascular disease.

Also: LDL

Topics Related to Low-Density Lipoprotein

Acetyl-L-Carnitine

...as a treatment
“...It is so effective in the process of burning fatty acids that it has shown the ability to register a marked decline in the bad cholesterol (LDL) levels, and simultaneously raise the good cholesterol (HDL) levels...”

Alcohol Consumption

...as a treatment
“...What would explain the apparent benefits of alcohol consumption?  ... Alcohol improves blood lipid profile by increasing HDL ("good") cholesterol and decreasing LDL ("bad") cholesterol...”
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More topics Related to Low-Density Lipoprotein

Arjun

...as a treatment
“...Arjun helps to normalize cholesterol levels; it increases the elimination of cholesterol by accelerating the turnover of LDL cholesterol in the liver...”

Atherosclerosis

...the condition
“...Risk factors include male gender, menopause in women, hypertension, elevated levels of low-density lipoprotein (LDL), decreased levels of high-density lipoprotein (HDL), quitting smoking, diabetes, obesity, having a personal or family history of heart disease, sedentary lifestyle...”
...recommendation Garlic
“A mechanism by which atherosclerotic plaque accumulates on the walls of arteries is the oxidation of LDL cholesterol...”

Biotin

...as a treatment
“...CIRCULATORY SYSTEM/BLOOD: Anemia, High cholesterol (LDL), Irregular heart beat...”

Bladderwrack

...as a treatment
“...According to test tube and animal studies, this appears to give fucoidan several properties, such as lowering LDL cholesterol levels, lowering blood glucose levels, anti-inflammatory activity, possible anticoagulant effects, and antibacterial and anti-HIV activity...”

Calcium-D-Glucarate

...as a treatment
“...Cholesterol Lowering Preliminary results in humans show that glucarate can significantly reduce total cholesterol, LDL and triglycerides...”

Cholesterol Level Check

...as a treatment
“...In addition, the National Cholesterol Education Program (NCEP) recommends routine measurement of a fasting lipoprotein profile (total cholesterol, LDL cholesterol, high density lipoprotein (HDL) cholesterol, and triglyceride) in all adults age 20 and older at least once every 5 years...”

Cigarette Smoke Damage

...relationship to Atherosclerosis
“...Specifically, these chemicals are carried in the bloodstream on LDL cholesterol, where they either damage the lining of the arteries directly or they damage the LDL molecule which then damages the arteries...”

Coffee

...as a treatment
“...Coffee also contains chemicals that increase low-density lipoproteins (LDL) in some people – the 'bad' cholesterol that leads to cardiovascular disease and contributes to artery clogging...”

Coronary Disease / Heart Attack

...the condition
“...Laboratory testing is now going far beyond total cholesterol (HDL and LDL ratios) and triglycerides...”
...our question about Low-carbohydrate dieting
“...clinical trial, despite statistically significant weight loss reported in the Atkins group, every single cardiac risk factor measured worsened after a year on the Atkins Diet (measures included LDL, triglycerides, total cholesterol, HDL, total-to-HDL cholesterol ratio, homocysteine, Lp(a), and fibrinogen)...”
...recommendation Policosanol/Octacosanol
“...One of policosanol's important actions is to inhibit the oxidation of LDL, which is the major contributor to arterial damage...”
...recommendation High/Increased Fiber Diet
“...In particular, soluble fiber alters and lowers fat and cholesterol absorption in the large bowel, helping to reduce LDL, the 'bad' cholesterol...”

Elevated Insulin Levels

...recommendation Chromium
“Chromium picolinate supplementation at 1,000mcg per day over a 13-week period combined with exercise decreased total cholesterol, LDL cholesterol and insulin levels in a recent small study of both males and females...”

Excess Animal Fat Consumption

...the condition
“...High levels of LDL cholesterol in the blood increase risk of heart disease and stroke...”

Gallbladder Disease

...the condition
“...One study found that within three days of the operation, levels of total cholesterol and LDL returned to their preoperative levels...”

Garlic

...as a treatment
“...Medical studies have shown that garlic can lower cholesterol, prevent dangerous blood clots, protect LDL cholesterol and the endothelial lining of the arterial system against oxidation, reduce blood pressure, prevent cancer, and protect against bacterial and fungal infections...”

Green Tea

...as a treatment
“...Reducing total cholesterol and LDL, it also increases the levels of positive cholesterol (HDL)...”

Gugulipids

...as a treatment
“...Gugulipid has been shown to effectively lower serum cholesterol and triglycerides, lower LDL and raise HDL levels...”

High Levels Of Triglycerides

...relationship to Coronary Disease / Heart Attack
“...triglycerides combined with low HDL (two abnormalities known to be caused by high insulin) are much more predictive of cardiovascular disease than either elevated total cholesterol or elevated LDL levels.”
...recommendation Vitamin B3 (Niacin)
“In a study of people with high cholesterol, niacin not only reduced LDL and triglycerides by 17% and 18% respectively, but it also increased HDL by 16%.”
...recommendation Digestive Enzymes
“Researchers found in 1997 that lipase can help to control LDL cholesterol and is helpful in stubborn cases of high triglycerides...”

High Total Cholesterol

...the condition
“...Three main types of lipoproteins exist ... LDL – low-density lipoprotein...”
...our question about Level of legume consumption
“...Legumes are rich in soluble fiber, which has been shown to help lower total cholesterol and LDL (''bad'') cholesterol levels, the study authors note...”
...relationship to Manganese Requirement
“See the link between Low HDL/LDL Cholesterol Ratio and Manganese Need.”
...recommendation Increased Legume Consumption
“...Legumes are rich in soluble fiber, which has been shown to help lower total cholesterol and LDL (''bad'') cholesterol levels, the study authors note...”
...recommendation Grain-free Diet
“...Minor cholesterol (LDL) reductions can be achieved by adding whole grains (especially oats) to the diet...”
...recommendation Melatonin
“Melatonin helps to decrease total cholesterol and "bad" LDL cholesterol levels.”
...recommendation Plant-Based Nutrition
“...49 observational and controlled studies found that plant-based vegetarian diets – especially vegan diets – are associated with lower levels of total cholesterol, including lower levels of HDL and LDL cholesterol, compared to omnivorous diets...”
...recommendation Garlic
“Several studies have shown a mild lowering effect on total cholesterol and LDL cholesterol...”
...recommendation Olive Oil
“Monounsaturated fatty acids – as contained in olive oil – reduce total and LDL cholesterol concentrations without reducing the levels of HDL cholesterol, thus leading to favorable changes in the serum lipid profile and possibly to changes in the physicochemical properties of...”
...recommendation Chromium
“...Chromium picolinate supplementation at 1,000mcg per day over a 13-week period combined with exercise decreased total cholesterol, LDL cholesterol and insulin levels in a recent small study of both males and females...”
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More topics Related to Low-Density Lipoprotein

Hypertension (High Blood Pressure)

...recommendation Garlic
“One study found that aged garlic extract at 7.2gm per day reduced total and LDL cholesterol, as well as systolic and diastolic blood pressure.”

Hyponatremia (Low Blood Sodium Level)

...the condition
“...Not enough salt can lead to various complications including ... Increased cholesterol (LDL) and Triglycerides...”

LDL/HDL Ratio, High

...the condition
“HDL and LDL are two different types of cholesterol that are measured as an index of a patient's risk for cardiovascular disease...”
...our question about Low-carbohydrate dieting
“The May 2004 Annals of Internal Medicine study showed that a third of Atkins Dieters suffered a significant increase in LDL cholesterol...”
...relationship to Manganese Requirement
“Manganese can help lower high triglyceride and cholesterol levels, with a particular effect on stabilizing LDL and decreasing its potential to form fatty plaques in the arteries.”
...relationship to Atherosclerosis
LDL is the cholesterol type most commonly thought of as a strong risk factor for atherosclerosis and heart disease...”
...recommendation Policosanol/Octacosanol
“Policosanol can lower LDL cholesterol as much as 20% and raise protective HDL cholesterol by 10%.”
...recommendation Melatonin
“Melatonin helps to decrease total cholesterol and "bad" LDL cholesterol levels.”
...recommendation Digestive Enzymes
“Researchers found in 1997 that lipase can help to control LDL cholesterol and is helpful in stubborn cases of high triglycerides...”
...recommendation Bladderwrack
“Alginic acid (a component of bladderwrack) may help lower LDL cholesterol levels, according to animal studies...”

Lycopene

...as a treatment
“...As reported in the journal Lipids, a group from Canada demonstrated that lycopene significantly lowers LDL oxidation in human blood...”

NADH

...as a treatment
“...Total cholesterol and LDL cholesterol were significantly reduced in the NADH group...”

Olive Leaf Extract

...as a treatment
“...More recent studies of oleuropein show that it seems to protect low density lipoprotein from oxidation, thus reducing the LDL (the bad cholesterol)...”

Peripheral Vascular Disease

...the condition
“...Risk factors for peripheral vascular disease are similar to those for atherosclerosis and include ... High LDL ("bad") cholesterol...”

Policosanol/Octacosanol

...as a treatment
“...Policosanol can lower LDL cholesterol by as much as 20% and raise protective HDL cholesterol by 10%...”

Poor Circulation

...the condition
“...If you don't know your cholesterol numbers yet, ask your doctor to measure your levels of "good" (HDL) and "bad" (LDL) cholesterol...”

Problems Associated With A Sedentary Lifestyle

...the condition
“...Potential adverse consequences of a sedentary lifestyle include ... increased LDL ('bad') cholesterol levels and risk of cardiovascular disease...”

Problems Caused By Being Overweight

...recommendation DHEA
“...At the same time, their LDL levels fell by 7.5% to confer protection against cardiovascular disease...”

Saturated Fat

...related topic
“A type of unhealthy fat that is readily converted to LDL cholesterol and is thought to encourage production of arterial disease...”

Soy Isoflavones

...as a treatment
“...Soy isoflavones have antioxidant properties which protect the cardiovascular system from oxidation of LDL (the bad) cholesterol...”

Test for Cardiac Risk Factors

...as a treatment
“...In fact, these two cholesterol particles have turned out to be more powerful predictive markers for a future fatal heart attack than levels of "good" (HDL) cholesterol, "bad" (LDL) cholesterol, total cholesterol, or triglycerides...”

Vitamin B3 (Niacin)

...as a treatment
“...It is an antioxidant nutrient that helps the body inhibit the formation of damaging free radicals; it lowers blood levels of LDL (bad) cholesterol and triglycerides...”

Vitamin E

...as a treatment
“...The major function of vitamin E is the protection from lipid peroxidation, an effect of free radical oxidation in membranes and LDL particles...”
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