Signs, symptoms & indicators of Cancer, General:
Conditions that suggest Cancer, General:
Risk factors for Cancer, General: |  |  |  | | Addictions | Cigarette Smoke Damage | Cigarette smokers have total, overall cancer death rates twice that of nonsmokers. The greater the number of cigarettes smoked, the greater the risk.
There is irrefutable evidence linking cigarette smoking and cancer of various sites. The urine of cigarette smokers has been found to be strongly mutagenic in bacterial test systems. There are at least 43 carcinogens described in cigarette smoke which include polyaromatic hydrocarbons, heterocyclic hydrocarbons, N-nitrosamines, aromatic amines, aldehydes, volatile carcinogens, inorganic compounds, and radioactive elements.
Cigarette smoke contains substances that act at every stage of cancer formation and growth. Organs that have direct contact with smoke (lung, oral cavity and esophagus) are at the greatest risk of developing cancer. As the substances delivered in cigarette smoke are absorbed and spread through the human body, smoking causes cancer at various distant sites. For example, cigarette smoking is a risk factor for the development of cervical cancer. Samples from the cervix of women smokers show components of tobacco smoke that contain mutagenic activity. |
| Family History |
Cancer in family members | Hormones |
Low Melatonin Level | People with higher levels of melatonin might be less likely to develop cancer, and people with lower levels seem to be more likely to develop at least some forms of cancer. At pharmacological levels (5-50mg), melatonin seems to be useful in fighting active cancers. Neither of these effects are huge - a lack of melatonin does not always cause cancer, and a large dose of melatonin does not always cure cancer. However, both effects seem large enough to be important. |
| Immunity |
Immune System Imbalance (TH2 Dominance) | Metabolic |
Problems Caused By Being Overweight | Apart from excess stimulation by estrogen in breast and ovarian cancer, obese people are more prone to cancer, although it is still uncertain why. |
| Nutrients |
Vitamin A Requirement | Analogues of vitamin A are known as retinoids. Numerous studies have shown that retinoid deficiency enhances the risk of cancer in humans. Retinoids are being used in humans to treat cancers (particularly skin, lung, bladder, cervical or breast) which involve epithelial tissues. Vitamin A can be used to both treat and prevent cancers and there have been a number of studies showing beta carotene's protective effects against cancer. |
| Supplements and Medications | Counter-indicators:
Selenium supplementation | Symptoms - Cancer |
History of cervical cancer
History of endometrial cancer | Symptoms - Environment |
(High) solvent exposure
(Heavy) treated lumber exposure | Symptoms - Food - Beverages |
(High) coffee consumption | Studies linking coffee consumption with cancer are conflicting and inconclusive at this point, but there is a suggestion of a higher incidence of cancers of the pancreas, ovaries, bladder, and kidneys in coffee drinkers. |
| Symptoms - Food - General |
Short-term/long-term low-carb dieting or discontinued low-carb diet | The American Cancer Society has officially condemned diets high in animal grease, concluding that "a low carb diet can be a high-risk option when it comes to health." [American Cancer Society. Weighing In on low carb Diets. 2004] |
| Symptoms - Food - Preferences |
(Partial) vegetarian diet or omnivorous diet | There has long been suspicion that components of meat and dairy were absorbed intact through the human digestive tract, triggering autoimmune disorders such as rheumatoid arthritis and childhood diabetes as our bodies try to fight off these foreign substances. In October of 2003, researchers published new evidence that a substance found in lamb, pork, beef and dairy can build up in human tissues and may contribute to chronic disease.
Taking autopsy samples, traces of a molecule called NeuGc can be found in human tissues, particularly in human tumors (especially breast cancer). Relatively high concentrations of anti-NeuGc antibodies can also be found in human blood. This mystified researchers, as human beings can not produce this substance. However, other animals can. Maybe, the researchers proposed, human beings absorb it from eating other animals.
The researchers adopted a vegan diet for a few days to clear their system (no animal-derived ingredients in foods or drugs or shampoo), and then drank a glass of "diluted pig mucus". Within days this invading meat molecule could be found oozing from their bodies, in their saliva, urine and hair clippings.
They speculate that this may why meat-eaters have such higher rates of cancer and heart disease compared to vegetarians. They acknowledge it could just be the saturated fat in meat and dairy, but maybe it is also because of the incorporation of this foreign substance (plants do not produce NeuGc). The researchers found it particularly interesting that vegetarian diets seem to improve rheumatoid arthritis. Maybe this reactive alien molecule also triggers autoimmune diseases like hepatitis and arthritis.
This article was published in the proceedings of the most prestigious scientific body in the United States. The researchers end their provocative article wondering what the long-term consequences might be of constantly challenging our immune systems in this way, and what the long-range implications are of having anti-Neu5Gc antibodies circulating throughout the bodies of meat-eaters and milk-drinkers. [Proceedings of the National Academy of Sciences 100 (2003): p.12045] |
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Cancer, General suggests the following may be present:
Cancer, General can lead to:
Recommendations and treatments for Cancer, General: |  |  |  | | Amino Acid / Protein | L-Arginine | Clinical studies have shown improved immune function in cancer patients fed arginine. |
Glutamine | Individuals with cancer who may be incapable of manufacturing their own supply of glutamine, may benefit from glutamine supplementats taken along with other amino acids. Recommendation: 1 scoopful (3-4gm) mixed with water 3-4 times daily; swish in mouth and swallow. Alternately 1,500-2,000mg in pills, 4 times a day. All doses taken between meals. |
Tyramine-containing Foods Avoidance | Only those using hydrazine sulfate are required to avoid tyramine-containing foods. |
| Animal-based |
Propolis | Bee propolis, a sticky resin collected by bees from trees, is a COX-2 inhibitor, according to Dr. Gaynor. Dr. Rao has found bee propolis very effective for cancer prevention in animals, noting "You can use it in lower doses than curcumin because it is highly absorbable." It is typically sold in 500mg capsules. |
| Botanical |
Bindweed | Bindweed inhibits new blood vessel development and thus restricts cancer growth. A typical dose is four to six 250mg capsules per day. Support for its use in cancer is currently limited to laboratory studies and personal experiences. |
Herbal Combinations | The essential ingredients of "C" Formula and "Y" Formula - CESSIAC(R) and YUCCALIVE(R) - include sheep sorrel, burdock root, schidigera yucca and fennel. The results of this group of observations, conducted in China, showed that the combined use of "C" Formula and "Y" Formula had confirmed therapeutic effect on the treatment and prevention of tumors. They could improve the immunologic function of the body and the overall health of the patient. The herbs had no obvious toxic side-effects. Information and study details can be found at the home page for Focus On Health.
Of the 39 cases in this study, 23 were tumor patients and 16 were secondary immunologic deficiency patients. Among the tumor patients, three died of advanced metastatic carcinoma since they were already at a critical stage when starting the treatment. There was one case of complete remission, 6 cases of partial remission and 13 cases of moderate remission and stabilized development. The total remission rate was 30.4%. The rate of moderate remission and stabilized development was 56.5% and the death rate 13%. Of the 16 secondary immunologic deficiency cases, 5 were notably benefitted, 8 were moderately benefitted, and three did not benefit.
Notably, there were no toxic side-reactions as seen with other anticancer drugs, such as arrest of bone marrow, digestive tract reactions and baldness. On the contrary, all patients in the study group had improvements in spirit, appetite, digestive function, physical strength and immunologic function of the body. The herbs were also shown to be effective on hepatitis B, allergic rhinitis, pulmonary tuberculosis and coronary heart disease. Therefore, the herbal combination was considered to be better than other antitumor drugs. |
Shiitake Mushrooms | The antitumor and anticancer properties of mushrooms have been studied. Shiitake (Lentinus edodes) and reishi (Ganoderma ludidum) have been found to have general anticancer and immune-stimulating activity [Gan To Kagaku Ryoho 1982;9(8): pp.1474-81]. Maitake (Grifolia frondosa) also contains immune-stimulating polysaccharides. There are some combination mushroom products on the market to help prevent and treat different forms of cancer. |
Kelp | Kelp and seaweed are anticancer agents, rich in the mucilagenous alginates which, like most fibers, gums and mucilages, swell in the intestines and absorb liquid as well as toxins and heavy metals. Alginates may also stimulate T-cell production and function since numerous other mucopolysaccharides have been shown to do this. Japanese studies show regular consumption of kelp reduces breast cancer risk. Kelp extracts have been highly successful in inhibiting laboratory cancer strains. |
Turmeric | Curcumin, the ingredient that gives turmeric its yellow color and one of the best studied of the natural COX-2 inhibitors, has been shown to inhibit the development of cancer in animals. Dr. Chintalapally V. Rao, a scientist with the American Health Foundation in Valhalla, New York, has conducted extensive animal studies with curcumin and notes that while the new drugs "undermine the activity of the COX-2 enzyme, curcumin completely blocks formation of the enzyme itself."
The intriguing evidence of curcumin’s anticancer effects in animal studies has prompted a clinical trial of the compound. Dr. Steven Schiff at Rockefeller University in New York is assessing whether curcumin supplements (250mg twice a day) can inhibit the development of colon cancer in humans.
As most of the cancer-inducing chemicals in cigarette smoke are only carcinogenic during the period between activation in the liver by Phase I and final detoxification by Phase II, curcumin in the turmeric can help prevent the cancer-causing effects of tobacco. Those exposed to smoke, aromatic hydrocarbons, and other environmental carcinogens will probably benefit from the frequent use of curry or turmeric. |
Rosemary | Rosemary is a COX-2 inhibitor, and increases the activity of detoxification enzymes. An extract of rosemary, called carnosol, has inhibited the development of both breast and skin tumors in animals. Rosemary can be used as a seasoning or a tea: Use 1tsp dried leaves per cup of hot water; steep for 15 minutes. |
| Detoxification |
Coffee Enema | Dr. Max Gerson pioneered the use of the coffee enema starting in the 1930s as part of a general detoxification regimen for cancer. Dr. Gerson noted some remarkable effects of this procedure including patients no longer needing pain-killers once on the enemas.
Dr. Lee Wattenberg, MD was able to show that substances found in coffee - kahweol and cafestol palmitate - promote the activity of a key enzyme system, glutathione S-transferase. This enzyme is responsible for neutralizing free radicals, harmful chemicals now commonly implicated in the initiation of cancer and needed for detoxification. Consuming coffee orally does not produce the benefits experienced when it is taken as an enema.
When cells are challenged by poisons, oxygen deprivation, malnutrition or a physical trauma they lose potassium, take on sodium and chloride, and swell up with excess water. This “tissue damage syndrome” makes it easier for cancerous cells to survive. Cells normally have a preference for potassium over sodium but when a cell is damaged it begins to prefer sodium.
This craving results in a damaged ability of cells to repair themselves and to utilize energy. Furthermore, damaged cells produce toxins. Around tumors are zones of "wounded" but still non-malignant tissue, swollen with salt and water. Dr. Gerson believed that cancer could not exist in normal metabolism. He directed his efforts toward creating normal metabolism in the tissue surrounding a tumor. |
| Diet |
Alcohol Consumption | Resveratrol is a potent COX-2 inhibitor produced in the skin of red grapes, where it protects against oxidation and fungal infections. Resveratrol is found in grape juice and red wine; red Bordeaux and French Cabernets contain a particularly high concentration of the compound. Resveratrol appears to help protect against cancer in at least three ways: It is anti-inflammatory, an antioxidant, and may prevent cancer cells from progressing to their next stage. Supplements provide about 600mcg of resveratrol, the amount found in a glass of red wine. |
Not recommended:
Therapeutic Fasting | Extended fasting should be avoided by patients with a current known cancer who have experienced significant weight loss. These patients tend to be malnourished already, and further nutrient restriction by fasting would make matters worse. |
| Drug |
Conventional Drug Use | COX-2 inhibitor drugs, so-called because they block an enzyme called cyclooxygenase-2 (COX-2), are used to treat pain and inflammation. There is now compelling evidence that they may also protect against cancer. Mitch Gaynor, MD, director of medical oncology at the Strang Cancer Prevention Center in New York, notes that suppressing COX-2 may be beneficial because "...the COX-2 enzyme helps make carcinogens much more active once they get into your body. The enzyme also allows cancerous cells to grow new blood vessels."
There may be drug-free alternatives to the synthetic COX-2 inhibitors as close as your spice shelf. Although they do not have as powerful an action, it appears that certain foods are natural inhibitors of the COX-2 enzyme. By incorporating these foods in your diet, you can obtain some of the potential cancer-preventing benefits of the COX-2 inhibitors naturally. |
Hydrazine Sulfate | Cachexia (wasting) in cancer patients is produced by the cancer cells’ partial metabolism of glucose, which leaves lactic acid as a by-product. The liver expends enormous amounts of the body’s energy converting lactic acid back to glucose. As the cancer grows (and puts out more and more lactic acid) this process is intensified, and the body weakens and wastes away. Hydrazine sulfate works by blocking a liver enzyme that catalyzes the conversion of lactic acid into glucose. This both stops the constant energy drain on the body and robs the tumor of a significant source of energy. |
| Hormone |
Melatonin | Melatonin has been shown to inhibit several types of cancer, especially hormone-related cancers like breast cancer and prostate cancer. This may be due to its ability to reduce the number of cellular estrogen receptors, which reduces the production of cell-multiplication factors. The immune-modulating properties of melatonin seem to convey additional anti-cancer properties. It has been shown to support the use of interleukin-2 in anti-cancer therapy, especially under conditions of controlled lighting. Many animal studies have demonstrated an increase in tumor growth rates in animals whose pineal glands have been removed.
Various researchers report successes against solid tumors, colorectal cancer, non-small cell lung cancer, brain metastases, glioblastoma, estrogen receptor-negative breast cancer, prostate cancer, metastatic renal cancer and adenocarcinoma of the pancreas. Furthermore, these effects seem to be substantial.
To select a typical example, people with solid tumors were given either just IL-2 (a regulator of the immune system), or IL-2 plus melatonin. 15% of the people receiving just IL-2 survived after one year, whereas 46% of the people also receiving melatonin survived. One researcher reported no failures i.e. instances in which melatonin did not have a positive effect. It has been proposed that melatonin might be useful for treating the general ill health found in cancer. |
| Lab Tests/Rule-Outs |
Test Copper Levels
Bacteria / Pathogen Testing by PCR | Oxygen / Oxidative Therapies |
Ozone / Oxidative Therapy | Physical Medicine |
Massage | It has been found at the James Cancer Hospital and Research Institute in Columbus, Ohio that cancer patients suffer less pain and anxiety after receiving therapeutic massage. |
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Preventive measures against Cancer, General: |  |  |  | | Botanical | Garlic
Chlorella
Green Tea | Green tea can delay or prevent the occurrence of some cancers, but typically must be consumed in large quantities (up to 10 cups or more) daily to achieve this effect. Extracts taken in pill form may be more convenient. |
| Diet |
High/Increased Fiber Diet | The Canadian Cancer Society recommends a higher fiber and lower fat diet to help lower the risk of cancer, especially colon and rectal cancers. Diets high in fiber are also rich in anti-cancer compounds such as anti-oxidants and phytochemicals found in fruits, vegetables and whole grains. |
Increased Fruit/Vegetable Consumption | Consumption of fruits is widely accepted as lowering the risk of most common cancers except prostate cancer. Many doctors recommend that people wishing to reduce their risk of cancer eat several pieces of fruit and several portions of vegetables every day. Optimal intakes remain unknown. |
Increased Fish Consumption | Study subjects who ate two or more servings of fish weekly had a much lower risk for esophageal, stomach, colon, rectum, and pancreatic cancers than those who avoided fish. In fact, the rates of these types of cancer were 30 to 50 percent lower among fish eaters. High fish consumption was also associated with lower risks for cancers of the larynx (30 percent lower risk), endometrial cancer (20 percent lower risk), and ovarian cancer (30 percent lower risk). |
Cabbage Family Vegetables | Cruciferous vegetables will reduce the risk of cancer in smokers, and most likely non-smokers as well. |
Coconut
Low/Decreased Fat Diet
Plant-Based Nutrition | "35 percent of cancer deaths may be related to diet." [The National Cancer Institute booklet "Diet, Nutrition, & Cancer Prevention: A Guide to Food Choices"]
Cancer rates for vegetarians are 25 to 50% below population averages, even after controlling for smoking, body mass index, and socioeconomic status.[1,2] Vegans show even better results. One study found that people who include generous amounts of fruits and vegetables in their daily diets have lower rates of cancers of the lung, breast, colon, bladder, stomach, mouth, larynx, esophagus, pancreas, and cervix compared to people who avoid such foods.[3]
Fruits and vegetables contain antioxidant substances, such as vitamin C, vitamin E, and carotenoids, which protect cells against oxidative damage, which is related to cancer risk and other health problems.[4] The multitude of phytochemicals found in various fruits, vegetables, grains, legumes, and nuts are thought to protect against heart disease and cancer.[5]
- Chang-Claude J, Frentzel-Beyme R, Eilber U. Mortality pattern of German vegetarians after 11 years of follow-up. Epidemiology 1992;3:395-401
- Thorogood M, Mann J, Appleby P, McPherson K. Risk of death from cancer and ischemic heart disease in meat and non-meat eaters. Brit Med J 1994;308:1667-70
- Block G. Epidemiologic evidence regarding vitamin C and cancer. Am J Clin Nutr 1991;54:1310S-4S
- Jacob RA, Burri BJ. Oxidative damage and defense. Am J Clin Nutr 1996;63:985S-90S
- Craig WJ. Phytochemicals: guardians of our health. J Am Diet Assoc 1997;97:S199-S204
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| Environmental |
Sunlight Exposure | Staying out of the sun completely may increase your chances of developing cancer, say doctors. For years, experts have advised people to cover up in the sun to protect themselves from skin cancer. A letter in the British Medical Journal (November, 2003) from professor Cedric Garland of the University of California warns people against taking this advice to the extreme. He says that a lack of sun can reduce levels of vitamin D, which may increase the risk of cancer. Studies have suggested that vitamin D can protect against colon, breast, prostate and other cancers. |
| Hormone |
DHEA | Mineral |
Selenium
Calcium-D-Glucarate | Nutrient |
Lycopene | A review of 72 studies [J Natl Cancer Inst 1999;91: pp.317-31] reported 57 associations between tomato intake or blood lycopene levels and decreased risk of cancer. Of these associations, 35 were statistically significant. The benefit was strongest for prostate, lung, and stomach cancers, although protective associations were also found for cancers of the pancreas, colon, rectum, esophagus, oral cavity, breast, and cervix. Because the data were from observational studies, a cause-and-effect relationship cannot be firmly established. However, the consistently lower risk of cancer associated with higher consumption of lycopene-containing tomatoes, provides a strong foundation for further research on lycopene.
One study found that for the 25% of people with the greatest tomato intake, the risk for cancers of the gastrointestinal tract was 30-60% lower, compared with those who ate fewer tomatoes. These reduced risks were statistically significant. [Int J Cancer 1994;59: pp.181-4] |
| Vitamins |
Vitamin D | Evidence of vitamin D's protective effect against cancer is compelling. For more than 50 years, documentation in medical literature suggests regular sun exposure is associated with substantial decreases in death rates from certain cancers and a decrease in overall cancer death rates. Recent research suggests this is a causal relationship that acts through the body's vitamin D metabolic pathways. For instance, some evidence points to a prostate, breast and colon cancer belt in the United States, which lies in northern latitudes under more cloud cover than other regions during the year. Rates for these cancers are two to three times higher than in sunnier regions.
Dark-skinned people require more sun exposure to make vitamin D. The thickness of the skin layer called the stratum corneum affects the absorption of UV radiation. Dark human skin is thicker than white skin and thus transmits only about 40% of the UV rays for vitamin D production. Darkly pigmented individuals who live in sunny equatorial climates experience a higher mortality (not incidence) rate from breast and prostate cancer when they move to geographic areas that are deprived of sunlight exposure in winter months. The rate of increase varies, and researchers hesitate to quote figures because many migrant black populations also have poor nutrition and deficient health care that confound statistics somewhat.
Although excessive sun exposure may give rise to skin cancer, researchers as early as 1936 were aware that skin cancer patients have reduced rates of other cancers. One researcher estimates moderate sunning would prevent 30,000 annual cancer deaths in the United States.
Vitamin D may also go beyond cancer prevention and provide tumor therapy. Much has been made of pharmaceutical angiogenesis inhibitors - agents that help inhibit the growth of new, undesirable blood vessels that tumors require for nutrient supply and growth. Laboratory tests have shown vitamin D to be a potent angiogenesis inhibitor.
Vitamin D also works at another stage of cancer development. Tumor cells are young, immortal cells that never grow up, mature and die off. Because vitamin D derivatives have been shown to promote normal cell growth and maturation, drug companies today are attempting to engineer patentable forms of vitamin D for anti-cancer therapy. |
Folic Acid |
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KEY |  | Weak or unproven link |  |  | Strong or generally accepted link |  |  | Proven definite or direct link |  |  | Weakly counter-indicative |  |  | May do some good |  |  | Likely to help |  |  | Highly recommended |  |  | Reasonably likely to cause problems |
GLOSSARY
Allergic Rhinitis (Hay Fever) Inflammation of the nasal mucous membranes that is caused by specific allergen(s). It is an allergy characterized by sneezing, itchy and watery eyes, a runny or stuffy nose, coughing and a burning/scratchy sensation of the palate and throat.
Amino Acid (Amino Acids) An organic acid containing nitrogen chemical building blocks that aid in the production of protein in the body. Eight of the twenty-two known amino acids are considered "essential," and must be obtained from dietary sources because the body can not synthesize them.
Antibody (Antibodies) A type of serum protein (globulin) synthesized by white blood cells of the lymphoid type in response to an antigenic (foreign substance) stimulus. Antibodies are complex substances formed to neutralize or destroy these antigens in the blood. Antibody activity normally fights infection but can be damaging in allergies and a group of diseases that are called autoimmune diseases.
Anti-inflammatory (Antiinflammatory) Reducing inflammation by acting on body mechanisms, without directly acting on the cause of inflammation, e.g., glucocorticoids, aspirin.
Antioxidant (Antioxidants) A chemical compound that slows or prevents oxygen from reacting with other compounds. Antioxidants are substances that protect cells from oxidative damage caused by molecules called free radicals. These chemicals can damage important parts of cells, such as proteins, membranes, and DNA. Some antioxidants have been shown to have cancer-protecting potential because they neutralize free radicals. Examples include vitamins C and E, beta carotene, the minerals selenium and germanium, superoxide dismutase (SOD), coenzyme Q10, catalase, and some amino acids.
Anxiety Apprehension of danger, or dread, accompanied by nervous restlessness, tension, increased heart rate, and shortness of breath unrelated to a clearly identifiable stimulus.
Arginine A nonessential amino acid but may be essential for individuals with certain diseases or nutritional concerns. May promote the release of growth hormone. Involved in creatine synthesis, a compound that stores energy in muscle. Helps to remove ammonia from the body as part of the urea cycle.
Arthritis (Arthritic) Inflammation of a joint, usually accompanied by pain, swelling, and stiffness, and resulting from infection, trauma, degenerative changes, metabolic disturbances, or other causes. It occurs in various forms, such as bacterial arthritis, osteoarthritis, or rheumatoid arthritis. Osteoarthritis, the most common form, is characterized by a gradual loss of cartilage and often an overgrowth of bone at the joints.
Autoimmune Disease (Autoimmune, Autoimmunity) One of a large group of diseases in which the immune system turns against the body's own cells, tissues and organs, leading to chronic and often deadly conditions. Examples include multiple sclerosis, rheumatoid arthritis, systemic lupus, Bright's disease and diabetes.
Bacteria (Bacterial, Bacterium) Microscopic germs. Some bacteria are "harmful" and can cause disease, while other "friendly" bacteria protect the body from harmful invading organisms.
Beta-Carotene (Beta Carotene) The most abundant of the carotenoids, beta-carotene has strong provitamin A activity and is a stronger antioxidant than vitamin A. It is widely accepted today as a cancer preventative. It is found in leafy green and yellow vegetables, often missing in children's diets. Beta-Carotene is believed to be a superior source of Vitamin A because it is readily converted into a more active form of the substance: your body converts it to Vitamin A as needed.
Biopsy Removal of a sample of tissue from a living being for diagnosis. A pathologist later uses a microscope to look for certain features, such as cancer cells, in the sample. A fine-needle aspiration biopsy involves inserting a thin needle to remove a small amount of tissue, sometimes using CT or ultrasound to guide the needle. A core biopsy involves obtaining a sample of tissue with a thick needle or by inserting a thin, lighted tube (laparoscope) into a small incision in the abdomen. Another biopsy method is to remove tissue during an operation.
Cachexia Weight loss due to chronic disease or prolonged emotional stress.
Cancer Refers to the various types of malignant neoplasms that contain cells growing out of control and invading adjacent tissues, which may metastasize to distant tissues.
Carcinogen (Carcinogenic, Carcinogenicity) Any agent that is cancer-causing.
Carcinoma Malignant growth of epithelial cells tending to infiltrate the surrounding tissue and giving rise to metastasis: An invasive malignant tumor derived from epithelial tissue that tends to metastasize to other areas of the body.
Cervix The lower part of the uterus that opens into the vagina.
Chemotherapy A treatment of disease by any chemicals. Used most often to refer to the chemical treatments used to combat cancer cells. Chemotherapy is usually given in cycles: a treatment period followed by a recovery period, then another treatment period, and so on. Most anticancer drugs are given by injection into a blood vessel (IV); some are given by mouth. Chemotherapy is a systemic therapy, meaning that the drugs enter the bloodstream and travel throughout the body. Usually, a patient has chemotherapy as an outpatient (at the hospital, at the doctor's office, or at home). However, depending on which drugs are given and the patient's general health, a short hospital stay may be needed.
Chronic (Chronicity) Usually referring to chronic illness: Illness extending over a long period of time.
Colon (Colonic) The part of the large intestine that extends to the rectum. The colon takes the contents of the small intestine, moving them to the rectum by contracting.
Colorectal Cancer A cancerous tumor of the large intestine. It is marked by dark, sticky stools containing blood and a change in bowel habits.
Crave (Craving, Cravings) To have a strong desire for; to feel the need for.
Cup (Cups) A unit of volume measurement equal to 8 fluid oz, or roughly 250ml. It also equals 1/2 pint, 1/4 quart and 1/16 gallon.
Diabetes Mellitus (Diabetes, Diabetic, Diabetics) A disease with increased blood glucose levels due to lack or ineffectiveness of insulin. Diabetes is found in two forms; insulin-dependent diabetes (juvenile-onset) and non-insulin-dependent (adult-onset). Symptoms include increased thirst; increased urination; weight loss in spite of increased appetite; fatigue; nausea; vomiting; frequent infections including bladder, vaginal, and skin; blurred vision; impotence in men; bad breath; cessation of menses; diminished skin fullness. Other symptoms include bleeding gums; ear noise/buzzing; diarrhea; depression; confusion.
Enzymes (Enzyme) Specific protein catalysts produced by the cells that are crucial in chemical reactions and in building up or synthesizing most compounds in the body. Each enzyme performs a specific function without itself being consumed. For example, the digestive enzyme amylase acts on carbohydrates in foods to break them down.
Epidemiology The study of the causes and distribution of disease in human populations.
Epithelial Referring to the cells that line and protect the external and internal surfaces of the body. Epithelial cells form epithelial tissues such as skin and mucous membranes.
Epstein Barr Virus (EBV, Epstein-Barr Virus) A virus that causes infectious mononucleosis and that is possibly capable of causing other diseases in immunocompromised hosts.
Esophagus (Esophageal) Commonly called the "food pipe", it is a narrow muscular tube, about nine and a half inches long, that begins below the tongue and ends at the stomach. It consists of an outer layer of fibrous tissue, a middle layer containing smoother muscle, and an inner membrane, which contains numerous tiny glands. It has muscular sphincters at both its upper and lower ends. The upper sphincter relaxes to allow passage of swallowed food that is then propelled down the esophagus into the stomach by the wave-like peristaltic contractions of the esophageal muscles. There is no protective mucosal layer, so problems can arise when digestive acids reflux into the esophagus from the stomach.
Estrogen (Oestrogen) One of the female sex hormones produced by the ovaries.
Free Radical (Free Radicals) A free radical is an atom or group of atoms that has at least one unpaired electron. Because another element can easily pick up this free electron and cause a chemical reaction, these free radicals can effect dramatic and destructive changes in the body. Free radicals are activated in heated and rancid oils and by radiation in the atmosphere, among other things.
Gastric Of, relating to, or associated with the stomach.
Gastrointestinal (GI, GI Tract) Pertaining to the stomach, small and large intestines, colon, rectum, liver, pancreas, and gallbladder.
Gland (Glands) The glandular system is one of the most important and complicated systems of the body. Gland tissue can be either an organ or general tissue that secretes chemicals and there are two types of gland: exocrine and endocrine. Those glands which secrete chemicals through tubules or ducts are called exocrine and include sweat, tear and salivary glands. Ductless glands - part of the endocrine system - secrete special chemicals (hormones) directly into the blood.
Glucose A sugar that is the simplest form of carbohydrate. It is commonly referred to as blood sugar. The body breaks down carbohydrates in foods into glucose, which serves as the primary fuel for the muscles and the brain.
Glutamine A "conditionally essential" amino acid, glutamine is considered to be a brain fuel. Glutamine has been used therapeutically for alcoholism, mild depression and to reduce the craving for sweets. Glutamine is very important in the functioning of the metabolism and muscle maintenance. Glutamine supplementation can help prevent muscle and other tissue breakdown by providing the body with nitrogen and fuel.
Glutathione A natural sulfur-bearing peptide formed from the linking of three amino acids: glutamic acid, cysteine and glycine. Glutathione acts as an antioxidant and detoxicant and is involved with the selenium-containing enzyme glutathione peroxidase. Glutathione is also involved in amino acid transport across cell membranes and is a powerful free radical scavenger and antioxidant that removes unwanted substances from the body.
Gram (gm, gms, Gramme, Grammes, Grams) A metric unit of weight, there being approximately 28 grams in one ounce.
Helicobacter Pylori (Pylori) H. pylori is a bacterium that is found in the stomach which, along with acid secretion, damages stomach and duodenal tissue, causing inflammation and peptic ulcers. Although most people will never have symptoms or problems related to the infection, they may include: dull, 'gnawing' pain which may occur 2-3 hours after a meal, come and go for several days or weeks, occur in the middle of the night when the stomach is empty and be relieved by eating; loss of weight; loss of appetite; bloating; burping; nausea; vomiting.
Hepatitis Inflammation of the liver usually resulting in jaundice (yellowing of the skin), loss of appetite, stomach discomfort, abnormal liver function, clay-colored stools, and dark urine. May be caused by a bacterial or viral infection, parasitic infestation, alcohol, drugs, toxins or transfusion of incompatible blood. Can be life-threatening. Severe hepatitis may lead to cirrhosis and chronic liver dysfunction.
Hepatitis B A serious viral infection with the potential for long term consequences. It is caused by a DNA virus that has been found in virtually all body secretions and excretions. However, only blood, saliva, semen and vaginal fluids have been shown to be infectious. Transmission occurs through sexual contact, blood-to-blood contact (blood products, needle sharing, etc.), and from infected mother to infant. Virtually all affected infants and children, and many adults, receive a lesser, even symptom-free, infection. Symptoms, when present, tend to be more severe and prolonged than those for Hepatitis A: initially flu-like, with malaise, fatigue, muscle pain and chest pain on the right side. This is followed by jaundice (slight skin yellowing), anorexia, nausea, fatigue, pale stools, dark urine and tender liver enlargement, but usually no fever.
Herbs (Herb, Herbal) Herbs may be used as dried extracts (capsules, powders, teas), glycerites (glycerine extracts), or tinctures (alcohol extracts). Unless otherwise indicated, teas should be made with one teaspoon herb per cup of hot water. Steep covered 5 to 10 minutes for leaf or flowers, and 10 to 20 minutes for roots. Tinctures may be used singly or in combination as noted. The high doses of single herbs suggested may be best taken as dried extracts (in capsules), although tinctures (60 drops four times per day) and teas (4 to 6 cups per day) may also be used.
IL-2 Interleukin-2.
Immune System (Immune Response, Immunity) A complex that protects the body from disease organisms and other foreign bodies. The system includes the humoral immune response and the cell-mediated response. The immune system also protects the body from invasion by making local barriers and inflammation. The process may involve acquired immunity (the ability to learn and remember a specific infectious agent), or innate immunity (the genetically programmed system of responses that attack, digest, remove, and initiate inflammation and tissue healing).
Ischemia (Ischemic) Localized tissue anemia due to obstruction of the inflow of arterial blood. A decrease in the blood supply to a bodily organ, tissue, or part caused by constriction or obstruction of the blood vessels.
Kidneys (Kidney, Renal) Bean-shaped organs, each about the size of a fist. They are located near the middle of the back, just below the rib cage. The kidneys are sophisticated reprocessing machines, each day handling about 50 gallons of blood to sift out about half a gallon of waste products and extra water. The waste and extra water become urine, which flows to the bladder through tubes called ureters. The actual filtering occurs in tiny units inside the kidneys called nephrons. Every kidney has about a million nephrons. In a nephron, a glomerulus -- which is a tiny blood vessel, or capillary -- intertwines with a tiny urine-collecting tube called a tubule. A complicated chemical exchange takes place, as waste materials and water leave your blood and enter your urinary system. The kidneys recycle chemicals such as sodium, phosphorus, and potassium and thus regulate their levels. Renal: Pertaining to the kidneys.
Larynx (Laryngeal, Voice Box) The short passageway shaped like a triangle that is just below the pharyx in the neck.
Liver (Hepatic) The largest and one of the most complex organs of the body, the liver is responsible for much of the metabolism of fats, proteins and carbohydrates. It is the site of much of the body's detoxification. It is connected very closely with digestion and the regulation of blood sugar, among many other functions. Found behind the ribs on the right side of the abdomen, it has many important functions such as removing harmful material from the blood, making enzymes and bile that help digest food, and converting food into substances needed for life and growth. Hepatic: Pertaining to the liver.
Lung (Lungs, Pulmonary) Organ of the body, located in the chest cavity which is designed to bring oxygen from the air into the blood stream, while also expelling carbon dioxide and other waste gases out of the body. Pulmonary: Related to the lungs.
Lymphoma (Lymphomas) Any tumor of the lymphatic tissues.
Malignant (Cancerous) Dangerous. Mainly used to describe a cancerous growth -- when used this way, it means the growth is cancerous and predisposed to spreading.
Melatonin The only hormone secreted into the bloodstream by the pineal gland. The hormone appears to inhibit numerous endocrine functions, including the gonadotropic hormones. Research exists on the efficacy of melatonin in treating jet lag and certain sleep disorders. Dosages greater than l milligram have been associated with drowsiness, headaches, disturbances in sleep/wake cycles and is contraindicated in those who are on antidepressive medication. It also negatively influences insulin utilization.
Metabolism (Metabolic, Metabolize, Metabolizes, Metabolizing) The chemical processes of living cells in which energy is produced in order to replace and repair tissues and maintain a healthy body. Responsible for the production of energy, biosynthesis of important substances, and degradation of various compounds. Also defined as the sum total of changes in an organism in order to achieve a balance (homeostasis): Catabolic burns up, anabolic stores and builds up; the sum of their work is metabolism.
Metastasize (Metastases, Metastasized, Metastasizes, Metastasizing, Metastatic) Usually in reference to cancer: to spread, especially destructively.
Microgram (mcg, Micrograms, ug) 0.000001 or a millionth of a gram.
Milligram (mg, Milligrams) 0.001 or a thousandth of a gram.
Mucopolysaccharides (Mucopolysaccharide) Carbohydrates that act as support structures in connective tissue in the body.
Mucus (Mucous) The viscous, slippery substance that consists chiefly of mucin, water, cells, and inorganic salts and is secreted as a protective lubricant coating by cells and glands of the mucous membranes.
Mutagenic (Mutagenicity) Production of genetic alterations.
Oncology The study of cancer.
Ovary (Ovaries) Ovaries are about the size of an almond and lie on either side of the lower abdomen beside the uterus. They usually produce one egg each month and whether the egg is fertilized or not, the reproductive process follows a monthly cycle, with constant changes in various hormone levels, preparing another opportunity for conception. The ovary is responsible for most of the estrogen production in women. At menopause (sometime after middle-age), egg production ceases and hormone levels drop significantly.
Pancreas (Pancreatic) Opposite the liver and behind the stomach, the pancreas has two main functions - to manufacture various enzymes for digestion, and to release hormones to help control the body's use of carbohydrates. It releases insulin to help each cell absorb glucose to burn as energy. In this way, insulin controls the amount of sugar (glucose) in the blood. Proper pancreatic function is very important: too much, too little, or no insulin production can be life-threatening. Some of the chemicals released by the pancreas are not hormones, but stimulate other glands to make hormones. Once again, balance is necessary. Nutritional requirements for the pancreas are many. Research indicates that chromium vitamins C, E, B-complex, calcium, magnesium and potassium are especially important.
Pharmacological Involving the use of drugs.
Phytochemicals (Phytochemical) Substances such as vitamins and minerals that occur naturally in plants and have been shown in research to possibly prevent or cure disease.
Pineal (Pineal Gland) The pineal gland is a pea-sized organ at the center of the brain that is highly sensitive to light. Until recently, almost nothing was known about this gland. Darkness signals the pineal gland to release melatonin. This important hormone has been found to play a role in sexual function and energy levels in general. It is also a powerful antioxidant protecting the body from age-causing free radicals.
Potassium A mineral that serves as an electrolyte and is involved in the balance of fluid within the body. Our bodies contain more than twice as much potassium as sodium (typically 9oz versus 4oz). About 98% of total body potassium is inside our cells. Potassium is the principal cation (positive ion) of the fluid within cells and is important in controlling the activity of the heart, muscles, nervous system and just about every cell in the body. Potassium regulates the water balance and acid-base balance in the blood and tissues. Evidence is showing that potassium is also involved in bone calcification. Potassium is a cofactor in many reactions, especially those involving energy production and muscle building.
Propolis A resinous, waxy material collected by bees from the buds of trees.
Prostate The prostate gland in men that surrounds the neck of the bladder and the urethra and produces a secretion that liquefies coagulated semen.
Rheumatoid Arthritis A long-term, destructive connective tissue disease that results from the body rejecting its own tissue cells (autoimmune reaction).
Saliva (Salivary) The watery mixture of secretions from the salivary and oral mucous glands that lubricates chewed food and moistens the oral walls.
Saturated Fat (Saturated Fats) A type of unhealthy fat that is readily converted to LDL cholesterol and is thought to encourage production of arterial disease. Saturated fats tend to be solid or almost solid at room temperature. Among saturated fats are animal fats, dairy products, and such vegetable oils as coconut and palm oils. The American Heart Association recommends that we limit our saturated fat intake to below 7-10% of total calories. Those with coronary heart disease or an LDL cholesterol level over 100 mg/dL should limit themselves further.
Sodium An essential mineral that our bodies regulate and conserve. Excess sodium retention increases the fluid volume (edema) and low sodium leads to less fluid and relative dehydration. The adult body averages a total content of over 100 grams of sodium, of which a surprising one-third is in bone. A small amount of sodium does get into cell interiors, but this represents only about ten percent of the body content. The remaining 57 percent or so of the body sodium content is in the fluid immediately surrounding the cells, where it is the major cation (positive ion). The role of sodium in the extracellular fluid is maintaining osmotic equilibrium (the proper difference in ions dissolved in the fluids inside and outside the cell) and extracellular fluid volume. Sodium is also involved in nerve impulse transmission, muscle tone and nutrient transport. All of these functions are interrelated with potassium.
Stomach A hollow, muscular, J-shaped pouch located in the upper part of the abdomen to the left of the midline. The upper end (fundus) is large and dome-shaped; the area just below the fundus is called the body of the stomach. The fundus and the body are often referred to as the cardiac portion of the stomach. The lower (pyloric) portion curves downward and to the right and includes the antrum and the pylorus. The function of the stomach is to begin digestion by physically breaking down food received from the esophagus. The tissues of the stomach wall are composed of three types of muscle fibers: circular, longitudinal and oblique. These fibers create structural elasticity and contractibility, both of which are needed for digestion. The stomach mucosa contains cells which secrete hydrochloric acid and this in turn activates the other gastric enzymes pepsin and rennin. To protect itself from being destroyed by its own enzymes, the stomach’s mucous lining must constantly regenerate itself.
Syndrome A medical condition characterized by a collection of related symptoms (what the patient feels) and signs (what a doctor can observe or measure).
T-Cell (T-Cells) T cells are lymphocytes that are produced in the bone marrow and mature in the thymus. T cells are responsible for mediating the second branch of the immune system called "cellular immune response." T cells can live for months to years. This lymphocyte population is defined by the presence of a rearranged T-cell receptor.
Teaspoon (Teaspoons, tsp) Equivalent to 5cc (5ml).
Thyroid (Thyroid Gland) The thyroid gland is an organ with many veins, anchored around the front of the throat near the voice box. It is essential to normal body growth in infancy and childhood. It absorbs iodine from the diet and releases thyroid hormones - iodine-containing compounds that help govern the rate of the body's metabolism (its total life processes), affecting body temperature, and regulating protein, fat and carbohydrate catabolism in all cells. They keep up growth hormone release, skeletal maturation, and heart rate, force, and output. They promote central nervous system growth, stimulate the making of many enzymes, and are necessary for muscle tone and vigor. To a high degree, metabolism is regulated by the hormone thyroxine, which can be made by the thyroid if enough organic iodine is available. An enlarged thyroid gland that is not cancer is sometimes called goitre.
Tuberculosis Also known as TB, Consumption or "The White Plague", tuberculosis is an infectious disease caused by a bacterium called Mycobacterium tuberculosis, usually affecting the lungs but possibly also the brain, kidneys and bones. Patients may at first be symptom-free or experience a flu-like illness. In the secondary stage, there might be a slight fever, night sweats, weight loss, fatigue and various other symptoms, depending on the part of the body affected. Tuberculosis of the lung is usually associated with a dry cough that eventually leads to a productive cough with blood-stained sputum. There might also be chest pain and shortness of breath.
Tumor (Tumors, Tumour, Tumours) An abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function; a neoplasm. Literally, a swelling; in the past the term has been used in reference to any swelling of the body, no matter what the cause. However, the word is now being used almost exclusively to refer to a neoplastic mass, and the more general usage is being discarded.
Vegan (Veganism, Vegans) A person who consumes no animal products of any kind. In other words, vegans do not consume meat, fish, fowl, dairy products, eggs, honey, or products containing gelatin or any other animal-derived ingredients such as whey powder or food colorings.
Vegetarian (Lacto-Ovo-Vegetarian, Vegetarianism, Vegetarians) A person who consumes no meat, fish or fowl (chicken, turkey, etc.), but who may consume animal products such as dairy products (milk, cheese, butter, etc.), eggs or honey.
Virus (Viri, Viruses) Any of a vast group of minute structures composed of a protein coat and a core of DNA and/or RNA that reproduces in the cells of the infected host. Capable of infecting all animals and plants, causing devastating disease in immunocompromised individuals. Viruses are not affected by antibiotics, and are completely dependent upon the cells of the infected host for the ability to reproduce.
Vitamin A A fat-soluble vitamin essential to one's health. Plays an important part in the growth and repair of body tissue, protects epithelial tissue, helps maintain the skin and is necessary for night vision. It is also necessary for normal growth and formation of bones and teeth. For Vitamin A only, 1mg translates to 833 IU.
Vitamin C (Ascorbic Acid) A water-soluble antioxidant vitamin essential to the body's health. When bound to other nutrients, for example calcium, it would be referred to as "calcium ascorbate". As an antioxidant, it inhibits the formation of nitrosamines (a suspected carcinogen). Vitamin C is important for maintenance of bones, teeth, collagen and blood vessels (capillaries), enhances iron absorption and red blood cell formation, helps in the utilization of carbohydrates and synthesis of fats and proteins, aids in fighting bacterial infections, and interacts with other nutrients. It is present in citrus fruits, tomatoes, berries, potatoes and fresh, green leafy vegetables.
Vitamin D A fat-soluble vitamin essential to one's health. Regulates the amount of calcium and phosphorus in the blood by improving their absorption and utilization. Necessary for normal growth and formation of bones and teeth. For Vitamin D only, 1mcg translates to 40 IU.
Vitamin E An essential fat-soluble vitamin. As an antioxidant, helps protect cell membranes, lipoproteins, fats and vitamin A from destructive oxidation. It helps protect red blood cells and is important for the proper function of nerves and muscles. For Vitamin E only, 1mg translates to 1 IU.
Last updated: Aug 23, 2009
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