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Treatment & Prevention
Substances that reduce platelet aggregation include tocotrienols, shark liver oil, curcumin, gingko biloba, grape seed extract, grapes and grape juice, testosterone, Coumadin, fish oils, vitamin E at 300 IU or above, B6 at 150-200mg, EFAs, garlic, taurine and gugulipids.
Bromelain has been shown to decrease aggregation of blood platelets. It is an effective fibrinolytic agent but this action is more evident in purified fibrinogen solutions than in plasma.
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Conditions that suggest Platelet Aggregation (Clotting):
Risk factors for Platelet Aggregation (Clotting): | | | | | Circulation |  Mitral Valve Prolapse | The prolapsing mitral valve is known to damage platelets and increase their aggregation. This work has been confirmed in several studies. |
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KEY | | Weak or unproven link | | | Strong or generally accepted link |
GLOSSARY
Atherosclerosis
Common form of arteriosclerosis associated with the formation of atheromas which are deposits of yellow plaques containing cholesterol, lipids, and lipophages within the intima and inner media of arteries. This results in a narrowing of the arteries, which reduces the blood and oxygen flow to the heart and brain as well as to other parts of the body and can lead to a heart attack, stroke, or loss of function or gangrene of other tissues.
Cardiovascular
Pertaining to the heart and blood vessels.
Essential Fatty Acid (EFA, EFAs, Essential Fatty Acids)
A substance that the human body cannot manufacture and therefore must be supplied in the diet.
Fibrinolytic
Fibrinolytic activity: Clot removal.
IU (mIU, uIU)
International Unit: An arbitrarily defined but agreed upon unit that depends on what is being measured.
mIU: 0.001 or one thousandth of an IU.
uIU: 0.000001 or one millionth of an IU.
Liver (Hepatic)
The largest and one of the most complex organs of the body, the liver is responsible for much of the metabolism of fats, proteins and carbohydrates. It is the site of much of the body's detoxification. It is connected very closely with digestion and the regulation of blood sugar, among many other functions. Found behind the ribs on the right side of the abdomen, it has many important functions such as removing harmful material from the blood, making enzymes and bile that help digest food, and converting food into substances needed for life and growth. Hepatic: Pertaining to the liver.
Milligram (mg, Milligrams)
0.001 or a thousandth of a gram.
Platelet Aggregation
Platelets are the small, rather uniform fragments of large bone marrow cells that aid the blood in coagulation, hemostasis, inflammation, and thrombus formation. Mild subclotting and sticking is a common early condition that can lead to thrombosis, atherosclerosis, and strokes, and can be helped by an aspirin a day, better fat digestion, and Ceanothus.
Platelets (Platelet)
Cells that help the blood to clot.
Taurine
A nonessential amino acid but may be essential for individuals with certain diseases or nutritional concerns. May be needed for the proper development and maintenance of the central nervous system. Taurine's role in bile formation is important for fat metabolism and blood cholesterol control.
Testosterone
The principal male sex hormone that induces and maintains the changes that take place in males at puberty. In men, the testicles continue to produce testosterone throughout life, though there is some decline with age. A naturally occurring androgenic hormone.
Vitamin B6 (B6, B-6)
Influences many body functions including regulating blood glucose levels, manufacturing hemoglobin and aiding the utilization of protein, carbohydrates and fats. It also aids in the function of the nervous system.
Vitamin E
An essential fat-soluble vitamin. As an antioxidant, helps protect cell membranes, lipoproteins, fats and vitamin A from destructive oxidation. It helps protect red blood cells and is important for the proper function of nerves and muscles. For Vitamin E only, 1mg translates to 1 IU.
Last updated: Jan 03, 2010
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